This paper illustrates how an emulator (or meta-model) of a tsunami code can be a useful tool to evaluate or qualify tsunami hazard levels associated with both specific and unknown tsunamigenic seismic sources.The meta-models are statistical tools permitting to drastically reduce the computational time necessary for tsunami simulations.As a consequ
Temozolomide (TMZ), a DNA methylating agent, is the primary chemotherapeutic drug used in glioblastoma treatment.TMZ induces mostly N-alkylation adducts (N7-methylguanine VITAMIN C 1000MG TR and N3-methyladenine) and some O6-methylguanine (O6mG) adducts.Current models propose that during DNA replication, thymine is incorporated across from O6mG, pr
Background To cover soft tissue defects, the perforator-based AEG L7WC8632BI Built in Washer Dryer 8kg/4kg propeller flap offers the option to rotate healthy tissue into complex wounds.By rotating the flap, the perforator is torqued.As a result, perfusion changes are possible.Methods A retrospective data analysis of patients was done, who received
Background: Anterior cervical discectomy and fusion (ACDF) sacrifices segmental mobility, which can lead to the acceleration of adjacent segment degeneration.The challenge has promoted cervical artificial disc replacement (CADR) as a substitute for ACDF.However, CADR has revealed a series of new issues that are not found in ACDF, such as hypermobil